Rupanex 10

Tablet
Generics: Rupatadine Fumarate 10mg
Category : Prescription Medicines Availability : In Stock Company : Sharif Pharmaceuticals Ltd.
You get 7% off in Prescription Medicines
Price

৳100.30

Required Prescription

Leaflet Rupatadine is used to treat the symptoms of seasonal and perennial allergic rhinitis, as well as urticaria.

Rupanex 10

Pharmacology 


Rupatadine is a non-sedative antagonist of histamine H1-receptors with a lengthy half-life. It also inhibits platelet activating factor (PAF) (PAF). Histamine and PAF both produce broncho constriction, which increases vascular permeability and serves as a mediator in the inflammatory process. Rupatadine has a better therapeutic impact than a single antihistamine because of its dual mechanism of action. Rupatadine also inhibits mast cell degranulation triggered by immunological and non-immune stimuli, as well as the release of cytokines, particularly tumor necrosis factor alpha (TNF), in human mastocytes and monocytes. 

  

Dosage & Administration 


Adults and adolescents (over 12 years): The recommended dose is 10 mg once a day. Rupatadine may be taken with or without food. 

Children aged 2 to 11 years: 

  • Children weighing 25 kg or more: 1 teaspoonful (5 ml) of the oral solution once daily with or without food. 

  • Children weighing equal or more than 10 kg to less than 25 kg: 1/2 teaspoonful (2.5 ml) oral solution once daily with or without food. 

  

Interaction 


When taking Rupatadine 20 mg with ketoconazole or erythromycin at the same time, the systemic exposure is increased. When these drugs, as well as other inhibitors of the CYP3A4 isozyme, are used together, rupatadine should be used with caution. When used with statins, CNS depressants, or alcohol, rupatadine should be used with caution. 

Grapefruit and grapefruit juice should not be eaten at the same time as Rupatadine. 

  

Contraindications 


Hypersensitivity to Rupatadine or to any of the excipients. 

  

Side Effects 


Asthenia, dizziness, and drowsiness are all common symptoms. Uncommon: Increased appetite, arthralgia, back pain, dizziness, constipation, cough, diarrhea, dry throat, epistaxis, fever, gastrointestinal discomfort, increased risk of infection, irritability, malaise, myalgia, nasal dryness, nausea, oropharyngeal pain, rash, thirst, vomiting, weight gain Palpitations and tachycardia are uncommon. 

  

Pregnancy & Lactation 


There are no clinical studies on the effects of Rupatadine on a pregnant woman. Rupatadine should not be used by pregnant women unless the possible benefit outweighs the risk to the baby. There is no information on whether Rupatadine is excreted in breast milk. As a result, it should not be used during nursing unless the benefits to the mother outweigh the danger to the newborn. 

  

Precautions & Warnings 


Asthenia, dizziness, and drowsiness are all common symptoms. Uncommon: Increased appetite, arthralgia, back pain, dizziness, constipation, cough, diarrhea, dry throat, epistaxis, fever, gastrointestinal discomfort, increased risk of infection, irritability, malaise, myalgia, nasal dryness, nausea, oropharyngeal pain, rash, thirst, vomiting, weight gain Palpitations and tachycardia are uncommon. 

  

Therapeutic Class 


Non-sedating antihistamines 

  

Storage Conditions 


Store in cool & dry place below 30°C, protect from light & moisture. Keep out of reach of children. 

 

 

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