Rupoma 10

Tablet
Generics: Rupatadine Fumarate 10mg
Category : Prescription Medicines Availability : In Stock Company : GENERAL Pharmaceuticals Ltd.
You get 7% off in Prescription Medicines
Price

৳100.00

Required Prescription

Leaflet Rupatadine is demonstrated for the symptomatic treatment of Regular & Lasting Unfavorably susceptible Rhinitis and Urticaria.

Rupoma 10

Pharmacology 

  

Rupatadine could be a long-acting, non-sedative opponent of histamine H1-receptors. It too antagonizes the platelet actuating figure (PAF). Both histamine and PAF cause broncho constriction which leads to an increment within the vascular penetrability and act as a go between within the fiery handle. With the double mode of activity, Rupatadine appears superior restorative impact than a confined antihistamine. Rupatadine has other against unfavorably susceptible properties such as the hindrance of the degranulation of pole cells initiated by immunological and non-immunological jolts and restraint of the discharge of cytokines, especially of the tumor rot figure alpha (TNF α) in human mastocytes and monocytes. 

  

Dosage & Administration 

  

Adults and adolescents (over 12 years): The recommended dose is 10 mg once a day. Rupatadine may be taken with or without food. 
 
Children aged 2 to 11 years: 

  • Children weighing 25 kg or more: 1 teaspoonful (5 ml) of the oral solution once daily with or without food. 

  • Children weighing equal or more than 10 kg to less than 25 kg: 1/2 teaspoonful (2.5 ml) oral solution once daily with or without food. 

  

Interaction 

  

With medicine: The concomitant administration of Rupatadine 20 mg and ketoconazole or erythromycin increases the systemic exposure. Rupatadine should be used with caution when it is administered concomitantly with these drug substances and other inhibitors of the isozyme CYP3A4. Rupatadine should be used with caution when it is co-administered with statins, CNS depressants or alcohol. 
 
With food: Grapefruit and Grapefruit juice should not be taken simultaneously with Rupatadine 

  

Contraindications 

  

Hypersensitivity to Rupatadine or to any of the excipients. 

  

Side Effects 

  

Common: Asthenia, discombobulation, laziness. Exceptional: Craving expanded, arthralgia, back torment, concentration impeded, stoppage, hack, the runs, dry throat, epistaxis, fever, gastrointestinal distress, expanded chance of contamination, fractiousness, disquietude, myalgia, nasal dryness, sickness, oropharyngeal torment, hasty, thirst, spewing, weight expanded. Uncommon: Palpitations, tachycardia. 

  

Pregnancy & Lactation 

  

There is no clinical data available on the exposure of Rupatadine during pregnancy. Pregnant women should therefore not use Rupatadine unless the potential benefit outweighs the potential risk for the infant. No information is available, whether Rupatadine is excreted in the mother's milk. Therefore, it should not be used during lactation, unless the potential benefits for the mother justify the potential risk to the infant. 

  

Precautions & Warnings 

  

Rupatadine should be used with caution in patients with known prolongation of the QT interval, patients with uncorrected hypokalemia, and patients with ongoing proarrhythmic conditions, such as clinically significant bradycardia or acute myocardial ischemia. Rupatadine should be used with caution in elderly patients (65 years and older). As there is no clinical experience in patients with impaired kidney or liver function, the use of Rupatadine 10 mg tablets is at present not recommended in these patients. 

  

Therapeutic Class 

  

Non-sedating antihistamines 

  

Storage Conditions 

  

Protect from light and moisture by storing below 30°C. Keep the medicine out of children's reach. 

 

 

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