Pharmacology of Cardobis 5 Tablet 

The most selective ß1 blocker is Bisoprolol Hemifumarate. It has the greatest affinity for the ß1 receptor of any beta-blocker currently on the market. Blocks the ß1 adrenergic receptor in the heart and vascular smooth muscle, lowering heart rate and cardiac output and lowering arterial blood pressure. In patients with non-ß1 selective ß1-blockers, ß-blockers can influence lipid metabolism, however Bisoprolol does not produce any changes in the cholesterol fraction, including the cardioprotective HDL-cholesterol, over long-term treatment.  

Dosage & Administration of Cardobis 5 Tablet 

Hypertension: Bisoprolol dosage must be tailored to the patient's specific needs. The recommended beginning dose is 5 mg once a day. 2.5 mg may be an acceptable beginning dosage for certain individuals. If the antihypertensive impact of 5 mg is insufficient, the dose can be raised to 10 mg, then to 20 mg once day if necessary. 

Angina: Usually 10 mg once daily (5 mg may be sufficient in certain individuals), with a maximum dose of 20 mg per day. 

Heart Failure: 1.25 mg once daily (in the morning) for 1 week, then 2.5 mg once daily for 1 week, then 3.75 mg once daily for 1 week, then 5 mg once daily for 4 weeks, then 7.5 mg once daily for 4 weeks, then 10 mg once daily for 4 weeks, then 10 mg once daily for 4 weeks, then 10 mg once daily for 4 weeks, then 10 mg once daily for 4 weeks, then 10 mg once daily for 4 weeks, then 10 mg once daily for 4 weeks, then 10 mg once 

Interaction of Cardobis 5 Tablet 

Other ß-blocking medications should not be used with bisoprolol. 

Contraindications 

Right ventricular failure related to pulmonary hypertension and sinus bradycardia in individuals with cardiogenic shock, overt heart failure, second- or third-degree A-V block, and sinus bradycardia. 

Side Effect of Cardobis 5 Tablet 

It is possible to have gastrointestinal problems, bradycardia, hypotension, headache, tiredness, sleep disturbances, dizziness, vertigo, thrombocytopenia, vision disturbances, and alopecia. 

Pregnancy & Lactation 

Bisoprolol's safety during pregnancy has yet to be determined. Lactation data isn't available. 

Precautions & Warnings 

During long-term bisoprolol therapy, renal, hepatic, and hematologic function should be monitored at regular intervals. 

Therapeutic Class 

Anti-adrenergic medicines (Beta blockers), medications that block beta-adrenoceptors, and beta-blockers 

Storage Conditions 

Keep away from light and heat in a dry area. Keep out of children's reach.